Tomivosertib HCl

SKU: orb1739356

Description

Tomivosertib (eFT508) is a selective MNK1/2 inhibitor that blocks the phosphorylation of eIF4E, thereby modulating the translation of mRNAs involved in oncogenesis and immune response. It has demonstrated activity in preclinical in vitro and in vivo models of cancer and inflammation.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1849590-02-8
• MW: 376.845
• Formula: C₁₇H₂₁ClN₆O₂
• SMILES: Cl.Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1
• Target: Others,MNK,PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118598855