Tomivosertib HCl

• Catalog Number: orb1739356
• Category: Small Molecules
• Description: Tomivosertib HCl
• Purity: 98.00%
• MW: 376.845
• Biological Activity: Tomivosertib, also known as eFT508 is a MNK1/2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1/2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling.
• CAS Number: 1849590-02-8
• Formula: C₁₇H₂₁ClN₆O₂
• SMILES: Cl.Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1
• Storage: -20°C
• Note: For research use only