Tolafentrine

SKU: orb2564669

Description

Tolafentrine is a dual PDE3/4 inhibitor used in research for pulmonary hypertension. It has shown efficacy in monocrotaline-induced rat models, improving hemodynamics, reducing right ventricular hypertrophy, and mitigating vascular remodeling in chronic studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 139308-65-9
• MW: 505.63
• Formula: C₂₈H₃₁N₃O₄S
• SMILES: O(C)C=1C=C2C([C@]3([C@@](N=C2C4=CC=C(NS(=O)(=O)C5=CC=C(C)C=C5)C=C4)(CCN(C)C3)[H])[H])=CC1OC
• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

65990