Tiotropium bromide

SKU: orb1309504

Description

Tiotropium bromide is a long-acting anticholinergic agent that antagonizes muscarinic M3 receptors in the airways, leading to bronchodilation for COPD management. It is widely used in respiratory research, with applications in both in vitro receptor binding studies and in vivo models of obstructive lung disease to investigate bronchodilatory mechanisms.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 136310-93-5
• MW: 472.42
• Purity: 96.82% (May vary between batches)
• Formula: C₁₉H₂₂BrNO₄S₂
• SMILES: [Br-].C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1
• Target: AChR
• Solubility: PBS:50 mg/mL (105.84 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.23 mM);DMSO:55 mg/mL (116.42 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tiopropium, Tiotropium, Tiotropium Bromide, Tiotropium bromide, BA679 BR, mAChR, Muscarinic acetylcholine receptor, Inhibitor, inhibit

Compound Identifiers

PubChem CID

5487426