Tinlorafenib

SKU: orb1687202

Description

Tinlorafenib (PF-07284890) is an orally bioavailable, brain-penetrant small molecule inhibitor targeting oncogenic BRAF V600E and V600K mutants. It is a research tool for investigating BRAF-driven pathologies, including CNS and peripheral tumors, in both cellular and animal model systems.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2573781-75-4
• MW: 456.89
• Formula: C₁₉H₁₉ClF₂N₄O₃S
• SMILES: CC1=C2C(=CC=C1NC3=C(Cl)C(NS(CCCF)(=O)=O)=CC=C3F)N=CN(C)C2=O
• Target: Others,Raf,ERK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155434855