Tigilanol tiglate

SKU: orb1699130

Description

Tigilanol tiglate (EBC-46) is a small molecule activator of PKC/C1 domains that triggers immunogenic cell death via organelle stress, ATP depletion, and caspase activation. Its ability to enhance responses to immune checkpoint blockade has been demonstrated in preclinical in vivo models, supporting research in oncology and cancer immunotherapy.

Research Area

Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 943001-56-7
• MW: 562.65
• Formula: C₃₀H₄₂O₁₀
• SMILES: O(C([C@H](CC)C)=O)[C@@]12[C@@](C1(C)C)([C@@]3([C@]4([C@](CO)(O4)[C@@H](O)[C@@]5(O)[C@]([C@@]3(O)[C@H](C)[C@H]2OC(/C(=C/C)/C)=O)(C=C(C)C5=O)[H])[H])[H])[H]
• Target: PKC,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

92135637