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Tie-2 Antibody

SKU: orb3131623

Description

AMG-780 is a fully human IgG2 antibody targeting angiopoietin 1 (Ang1) with an IC50 of 4.5 nM and angiopoietin 2 (Ang2) with an IC50 of 0.06 nM. It inhibits tumor growth in Colo205 xenograft mouse models by suppressing Ang1 and Ang2. AMG-780 can be used in cancer research, such as for colorectal cancer.

Research Area

Signal Transduction

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
TargetTie-2
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Tie-2 Antibody (orb3131623)

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