Thiolutin

SKU: orb1685612

Description

Thiolutin (Acetopyrrothin) is a Streptomyces-derived small molecule with antibiotic and anti-angiogenic activity. It functions by inhibiting endothelial cell adhesion and rapidly inducing Hsp27 phosphorylation, making it a useful tool for studying angiogenesis and cellular stress responses in vitro.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 87-11-6
• MW: 228.29
• Purity: >99.99% (May vary between batches)
• Formula: C₈H₈N₂O₂S₂
• SMILES: CC(=O)Nc1c2sscc2n(C)c1=O
• Target: Pyroptosis,HMG-CoA Reductase,Antibacterial,NOD-like Receptor (NLR),DUB,Endogenous Metabolite,Antibiotic,DNA/RNA Synthesis
• Solubility: DMSO:4.5 mg/mL (19.71 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibiotic, Bacterial, Acetopyrrothin, Thiolutin

Compound Identifiers

PubChem CID

25271757