thermospermine

SKU: orb1301185

Description

Thermospermine is a spermine isomer that functions as a plant growth regulator, notably inhibiting xylem differentiation and modulating the translation of specific mRNAs like SAC51 in Arabidopsis. It is widely used in plant biology research to study developmental processes and control wood biomass production in both in vivo and in vitro experiments.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 70862-11-2
• MW: 202.34
• Purity: 99.11% (May vary between batches)
• Formula: C₁₀H₂₆N₄
• SMILES: NCCCCNCCCNCCCN
• Target: Others,DNA/RNA Synthesis
• Solubility: DMSO:55 mg/mL (271.82 mM)

Bioactivity

• In Vitro:
  The mutant defective in the biosynthesis of thermospermine, ACL5, shows a dwarf phenotype with excess xylem vessels in Arabidopsis thaliana. Exogenous supply of thermospermine remarkably represses xylem differentiation in the root of seedlings. Rice showed up-regulation of phloem-expressed genes, OsHB5 and OsYSL16, by one-day treatment with thermospermine.Expression of OsPAO2 and OsPAO6, encoding extracellular polyamine oxidase whose orthologs are not present in Arabidopsis, was induced by both thermospermine and spermine.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1,12-Diamino-4,8-diazadodecane, N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine, thermospermine

Compound Identifiers

PubChem CID

194365