Thalidomide-Piperazine-PEG2-NH2

SKU: orb1984582

Description

This synthetic E3 ligase ligand-linker conjugate incorporates a cereblon-binding thalidomide derivative connected via a piperazine-PEG2 linker. It serves as a key component for constructing PROTAC molecules, enabling targeted protein degradation in both cellular and biochemical research applications.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2357110-14-4
• MW: 473.53
• Formula: C₂₃H₃₁N₅O₆
• SMILES: NCCOCCOCCN1CCN(CC1)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1
• Target: Autophagy,Others,E3 Ligase Ligand-Linker Conjugates,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138694683