Thalidomide-Piperazine 5-fluoride

SKU: orb1909084

Description

Thalidomide-Piperazine 5-fluoride is a cereblon-directed E3 ligase ligand-linker conjugate, widely used in PROTAC development for targeted protein degradation. This compound serves as a key intermediate for constructing PROTAC molecules in biochemical and cellular research, facilitating the study of protein function in both in vitro and in vivo models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2222114-22-7
• MW: 360.34
• Formula: C₁₇H₁₇FN₄O₄
• SMILES: O=C1N(C(=O)C=2C1=CC(=C(F)C2)N3CCNCC3)C4C(=O)NC(=O)CC4
• Target: Others,E3 Ligase Ligand-Linker Conjugates,Apoptosis,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134413827