Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc

SKU: orb2945805

Description

This compound is a Thalidomide-based E3 ligase ligand conjugated to a PEG linker, designed for synthesizing PROTAC degraders like JB300. It serves as a key building block in chemical biology research for developing targeted protein degradation tools, applicable in both in vitro and cellular studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1957235-73-2
• MW: 562.569
• Formula: C₂₆H₃₄N₄O₁₀
• SMILES: O=C(OC(C)(C)C)NCCOCCOCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

140831850