Thalidomide-O-amido-PEG4-C2-NH2

SKU: orb1984677

Description

This compound is a thalidomide-based cereblon ligand conjugated to a flexible PEG4 linker, forming a key component for constructing PROTAC degraders. It serves as an E3 ubiquitin ligase recruiter in chemical biology research, enabling targeted protein degradation studies in both cellular and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1957236-22-4
• MW: 550.565
• Formula: C₂₅H₃₄N₄O₁₀
• SMILES: NCCOCCOCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
• Target: Others,E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121439758