Thalidomide-O-amido-C6-NH2 TFA

SKU: orb1307439

Description

Thalidomide-O-amido-C6-NH2 TFA

Research Area

Cell Biology, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1950635-14-9
• MW: 1087.95
• Purity: 95.16% (May vary between batches)
• Formula: C₄₆H₅₃F₆N₈O₁₆
• SMILES: O=C(NCCCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)FC1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCCCCCN.C(=O)(C(F)(F)F)O
• Target: Apoptosis,Autophagy,Ligands for E3 Ligase,E3 Ligase Ligand-Linker Conjugates,PROTAC Linker
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (4.6 mM);DMSO:105.5 mg/mL (96.97 mM)

Bioactivity

• In Vitro:
  PROTACs consist of two ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other targeting the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

E3 Ligase Ligand-Linker Conjugates 25, E3 Ligase Ligand-Linker Conjugates 25 TFA, E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate, E3 Ligase Ligand-Linker Conjugates, Cereblon, Cereblon Ligand-Linker Conjugates 11, Cereblon Ligand-Linker Conjugates 11 TFA, inhibit, Inhibitor, Ligand for E3 Ligase, LigandforE3Ligase, Thalidomide O amido C6 NH2 TFA, ThalidomideOamidoC6NH2 TFA, Thalidomide-O-amido-C-6-NH2 TFA, Thalidomide-O-amido-C6-NH2 TFA

Quick Database Links

Gene Symbol

Apoptosis,Autophagy,Ligands for E3 Ligase,E3 Ligase Ligand-Linker Conjugates,PROTAC Linker