Thalidomide-O-amido-C4-NH2 TFA

SKU: orb1299533

Description

This compound is a synthetic E3 ligase ligand-linker conjugate incorporating a thalidomide derivative. It is designed for use in PROTAC development and targeted protein degradation research, applicable in both cellular and biochemical in vitro studies.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1799711-25-3
• MW: 516.42
• Purity: 95.00% (May vary between batches)
• Formula: C₂₁H₂₃F₃N₄O₈
• SMILES: O=C(NCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F
• Target: Apoptosis,Autophagy,E3 Ligase Ligand-Linker Conjugates
• Solubility: DMSO:40 mg/mL (77.46 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.87 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cereblon Ligand-Linker Conjugates 6 TFA, Cereblon Ligand-Linker Conjugates 6, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugates, E3 Ligase Ligand-Linker Conjugate, E3 ligase Ligand-Linker Conjugates 19, E3 ligase Ligand-Linker Conjugates 19 TFA, E3LigaseLigandLinkerConjugate, inhibit, Inhibitor, Thalidomide O amido C4 NH2 TFA, ThalidomideOamidoC4NH2 TFA, Thalidomide-O-amido-C-4-NH2 TFA, Thalidomide-O-amido-C4-NH2 TFA

Compound Identifiers

PubChem CID

121410950