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Thalidomide-O-amido-C3-NH2

SKU: orb1984668

Description

Thalidomide-O-amido-C3-NH2 is a cereblon (CRBN)-directed ligand-linker conjugate for constructing PROTACs. It serves as a key component in the development of bifunctional degraders for targeted protein elimination in biochemical and cellular research, applicable in both in vitro and in vivo experimental settings.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2022182-57-4
MW388.37
FormulaC18H20N4O6
SMILESO=C(NCCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
TargetAutophagy,Others,E3 Ligase Ligand-Linker Conjugates,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Thalidomide-O-amido-C3-NH2 (orb1984668)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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