Thalidomide-NH-PEG1-NH2 hydrochloride

SKU: orb1298119

Description

This compound is a synthetic PROTAC linker conjugate featuring a thalidomide-based cereblon ligand. It is widely used in chemical biology and drug discovery research to develop PROTAC molecules for targeted protein degradation in both cellular and preclinical models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2154342-56-8
• MW: 396.83
• Purity: 97.13% (May vary between batches)
• Formula: C₁₇H₂₁ClN₄O₅
• SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCN)=O.[H]Cl
• Target: Autophagy,E3 Ligase Ligand-Linker Conjugates,Apoptosis

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Thalidomide NH PEG1 NH2 hydrochloride, ThalidomideNHPEG1NH2 hydrochloride, Thalidomide-NH-PEG-1-NH2 hydrochloride, Thalidomide-NH-PEG1-NH2 Hydrochloride, 4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl, E3 Ligase Ligand-Linker Conjugates, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, E3LigaseLigandLinkerConjugate, Inhibitor, inhibit

Compound Identifiers

PubChem CID

154828688