Thalidomide-NH-C10-Boc

SKU: orb2665494

Description

Thalidomide-NH-C10-Boc (S20) is a versatile PROTAC linker-conjugate that incorporates a Cereblon E3 ligase ligand. It enables the construction of bifunctional degraders, such as dCE-2 for targeting EP300/CBP, and is used in chemical biology and targeted protein degradation research both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2428400-25-1
• MW: 513.63
• Formula: C₂₈H₃₉N₃O₆
• SMILES: O=C(OC(C)(C)C)CCCCCCCCCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154675613