Tetrahydroberberine

SKU: orb1224807

Description

Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber; has micromolar affinity for dopamine D(2) (pK(i) = 6.08) and 5-HT(1A) (pK(i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors (5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK(i) < 5.00).

Images & Validation

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Key Properties

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CAS Number	522-97-4
MW	339.39
Purity	>98% (HPLC)
Formula	C₂₀H₂₁O₄N
SMILES	COC1=C(OC)C2=C(CC3N(CCC4=CC5=C(OCO5)C=C34)C2)C=C1
Target	5-HT Receptor
Solubility	DMSO: 10 mM

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

5-HT Receptor

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