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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

SKU: orb1984528

Description

Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes, demonstrates potent in vitro anti-HIV activity, and improves in vivo pharmacokinetic properties.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number2611373-74-9
MW626.855
FormulaC29H55N6O5PSi
SMILESN.C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCOCCCCCCCCCCCCC#C[Si](C)(C)C
TargetOthers,HIV Protease

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium (orb1984528)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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