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Tenapanor

SKU: orb1299683

Description

Tenapanor

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1234423-95-0
MW1145.05
Purity99.49%
FormulaC50H66Cl4N8O10S2
SMILESCN1C[C@@H](c2cccc(c2)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c2cccc(c2)[C@@H]2CN(C)Cc3c(Cl)cc(Cl)cc23)c2cc(Cl)cc(Cl)c2C1
TargetSodium Channel
SolubilityH2O:< 0.1 mg/mL (insoluble);DMSO:150 mg/mL (131 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.75 mM)

Bioactivity

Target IC50
NHE3 (rat):10 nM IC50 |NHE3 (human):5 nM IC50

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

Sodium/hydrogen Exchanger, Sodium Channel, SodiumChannel, Sodium-hydrogen Exchanger, Tenapanor, Tenapanor free base, phosphate absorption, RDX 5791, RDX5791, RDX-5791, hyperphosphatemia, Na+/H+ Exchanger (NHE), intestinal, AZD 1722, AZD1722, AZD-1722

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Key Properties

No computed properties available.

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Tenapanor (orb1299683)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
10 mg
$ 160.00
25 mg
$ 290.00
1 ml x 10 mM (in DMSO)
$ 360.00
50 mg
$ 430.00
100 mg
$ 630.00
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