Telomerase-IN-2

SKU: orb1309020

Description

Telomerase-IN-2 is a potent small molecule inhibitor of telomerase, exhibiting an IC50 of 0.89 µM through downregulation of dyskerin expression. This compound is a valuable research tool for investigating telomerase biology and its role in cellular aging and oncology, applicable in both in vitro and in vivo experimental models.

Research Area

Molecular Biology

Key Properties

• CAS Number: 1610878-54-0
• MW: 633.69
• Purity: 99.32% (May vary between batches)
• Formula: C₃₄H₃₉N₃O₉
• SMILES: COc1cc(OC)c2c(c1)oc(-c1cc(OC)c(OC)c(OC)c1)c(OCCCCN1CCN(CC1)C(=O)c1ccncc1)c2=O
• Target: Telomerase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.89 mM);DMSO:235 mg/mL (370.84 mM)

Bioactivity

• Target IC50:
  Telomerase:0.89 µM
• In Vitro:
  Telomerase-IN-2 exhibits high activity against Hela, SMMC-7721, SGC-7901, U87 and HepG2 cell lines in the anticancer activity assay in vitro.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Telomerase, Telomerase IN 2, Telomerase inhibitor 2, TelomeraseIN2, Telomerase-IN-2, inhibit, Inhibitor

Compound Identifiers

PubChem CID

76285870