TDK-HCPT

SKU: orb2944549

Description

TDK-HCPT is a glutathione-responsive small molecule conjugate that delivers 10-hydroxycamptothecin into tumor cells, prolongs its intracellular retention, and induces apoptosis. It demonstrates antitumor efficacy in both in vitro cytotoxicity assays and in vivo xenograft models, making it a candidate for targeted chemotherapy research.

Research Area

Cell Biology

Key Properties

• MW: 872.145
• Formula: C₄₂H₅₃N₃O₉S₄
• SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)OC(=O)CCCSC(C)(C)SCCCC(=O)OCC/C(=C(\C)/N(C)C=O)/SSCC(C)C)O
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677093