TAS-117 hydrochloride

SKU: orb1687135

Description

TAS-117 hydrochloride is a potent, orally bioavailable allosteric inhibitor of Akt isoforms, with highest potency against Akt2. It demonstrates anti-myeloma activity in research, enhancing proteasome inhibitor-induced ER stress to promote apoptosis and autophagy in preclinical studies.

Research Area

Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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MW	460.96
Formula	C₂₆H₂₅ClN₄O₂
Target	Autophagy,Others,Akt,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Autophagy,Others,Akt,Apoptosis

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