Talotrexin ammonium

SKU: orb1685749

Description

Talotrexin ammonium is a non-polyglutamatable antifolate that potently inhibits dihydrofolate reductase (DHFR). Its mechanism of action has demonstrated anti-tumor efficacy in various in vitro and in vivo cancer models, making it a valuable research tool for oncology and enzymology studies.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 648420-92-2
• MW: 590.59
• Purity: 97.13% (May vary between batches)
• Formula: C₂₇H₃₀N₁₀O₆
• SMILES: NC=1C2=C(N=CC(CNC3=CC=C(C(N[C@@H](CCCNC(=O)C4=C(C(O)=O)C=CC=C4)C(O)=O)=O)C=C3)=N2)N=C(N)N1.N
• Target: Antifolate,Others,DHFR
• Solubility: DMSO:50 mg/mL (84.66 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DHFR

Compound Identifiers

PubChem CID

9938420