T0070907

SKU: orb1300552

Description

T0070907

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 313516-66-4
• MW: 277.66
• Purity: 99.98%
• Formula: C₁₂H₈ClN₃O₃
• SMILES: [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1
• Target: PPAR
• Solubility: DMSO:72.14 mg/mL (259.81 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.6 mM)

Bioactivity

• Target IC50:
  PPARα:0.85 μM (Ki)|PPARδ:1.8 μM (Ki)|PPARγ:1 nM
• In Vivo:
  T0070907 can attenuat the beneficial effects of lipopolysaccharide pretreatment, such as significantly improving renal insufficiency, reducing hepatocyte damage and circulatory failure, and reducing plasma interleukin-1 elevation caused by severe endotoxemia.
• Cell Research:
  MTS assay(Only for Reference)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, PPARδ, PPARγ, PPARα, PPAR, Peroxisome proliferator-activated receptors, T 0070907, T0070907, T-0070907

Compound Identifiers

PubChem CID

2777391