SZUH280

SKU: orb1982403

Description

SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC50 of 0.58 μM in A549 cells. It promotes cancer cell apoptosis, inhibits DNA damage repair, and acts as a radiosensitizer, making it a valuable tool for oncology research in both cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2770263-77-7
• MW: 706.7
• Formula: C₃₆H₃₄N₈O₈
• SMILES: N(CC1=CN(CCOCCOC2=CC=C(CN3C=4C(C=C3)=CC=C(C(NO)=O)C4)C=C2)N=N1)C5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642477