SZU-B6

SKU: orb2695624

Description

SZU-B6 is a potent and cell-active PROTAC degrader of SIRT6, demonstrating anti-proliferative, pro-apoptotic, and cell cycle arrest effects in hepatocellular carcinoma cells in vitro and anti-tumor efficacy in murine models in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3059333-98-8
• MW: 593.61
• Formula: C₂₉H₃₂FN₇O₆
• SMILES: O=C1C2=CC(F)=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCC(CN5CCN(C6=CC=C(C(N)=C6)N(=O)=O)CC5)CC4
• Target: PROTACs|||Sirtuin|||Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172562033