Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)

SKU: orb2277362

Description

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide with greater thrombin affinity than Hirugen, exhibiting a dissociation constant (K D) of less than 100 nM. This compound acts as an antithrombotic agent, effectively inhibiting thrombin-induced fibrin clot formation with an inhibitory concentration (IC 50) of 0.087 μM.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 131791-98-5
• MW: 1445.5
• Formula: C₆₄H₈₈N₁₀O₂₆S
• SMILES: C([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CCC(O)=O)=O)=O)CCC(O)=O)=O)CCC1)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(OS(=O)(=O)O)C=C4)C(N[C@H](C(N[C@H](CCC(O)=O)C(O)=O)=O)CC(C)C)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC3
• Target: Thrombin

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

101596497