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STL127705

SKU: orb1309055

Description

STL127705

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1326852-06-5
MW437.42
Purity97.41%
FormulaC22H20FN5O4
SMILESCOc1ccc(CCNc2ncc3c(n2)[nH]c(=O)n(-c2cccc(F)c2)c3=O)cc1OC
TargetDNA-PK,Apoptosis
SolubilityH2O:< 0.1 mg/mL (insoluble);DMSO:11.54 mg/mL (26.38 mM)

Bioactivity

Target IC50
DNA-PKCS:2.5 μM |Ku 70/80:3.5 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anticancer, antiproliferative, Apoptosis, 7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione, Compound L, DNA-dependent protein kinase, DNAPK, DNA-PK, DNA-PKCS, DNA-PKCS kinase, inhibit, Ku 70/80, Ku 70/80 heterodimer protein, Inhibitor, H1299 cells, SF-767 cells, STL 127705, STL127705, STL-127705
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

STL127705 (orb1309055)

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Available Sizes

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1 mg
$ 110.00
5 mg
$ 210.00
1 ml x 10 mM (in DMSO)
$ 230.00
10 mg
$ 290.00
25 mg
$ 460.00
50 mg
$ 660.00
100 mg
$ 850.00
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