ST-539

SKU: orb2944665

Description

ST-539 is a potent and selective USP30 deubiquitinase inhibitor (IC50 = 0.37 µM) that promotes mitochondrial protein ubiquitination to induce mitophagy. This activity makes it a valuable research tool for studying mitochondrial quality control in models of Parkinson's disease and other neurodegenerative disorders.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 1040754-67-3
• MW: 529.65
• Formula: C₃₀H₃₁N₃O₄S
• SMILES: O=C(NC(C(=O)NC1=CC=CC=2C1=CC=CC2S(=O)(=O)NC(C)(C)C)CC=3C=CC=CC3)C=4C=CC=CC4
• Target: DUB,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

4060978