SRT 1460

SKU: orb1299014

Description

SRT 1460

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 925432-73-1
• MW: 507.6
• Purity: 98.25%
• Formula: C₂₆H₂₉N₅O₄S
• SMILES: OC(=O)C(F)(F)F.COc1cc(cc(OC)c1OC)C(=O)Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1
• Target: Sirtuin
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.97 mM);DMSO:5.08 mg/mL (10.01 mM)

Bioactivity

• Target IC50:
  SIRT1:2.9 μM (EC1.5)
• In Vitro:
  SRT1460 inhibited cell growth and survival of pancreatic cancer cells.
• Cell Research:
  Patu8988t (pancreatic cancer cells), Panc-1 (pancreatic cancer cells), SU86.86 (pancreatic cancer cells), HPDE cells. Concentration:2 μM, 4 μM, 6 μM. Incubation Time:72 hours

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sirtuin, SIRT1, SRT 1460, SRT1460, SRT-1460, inhibit, Inhibitor

Compound Identifiers

PubChem CID

25232707