(S,R,S)-AHPC-PEG4-NH2

SKU: orb1707347

Description

This synthetic E3 ligase ligand-linker conjugate incorporates a VHL-targeting (S,R,S)-AHPC ligand connected via a tetraethylene glycol (PEG4) spacer. It serves as a key component in the construction of PROTACs and other bifunctional molecules for targeted protein degradation research, applicable in both cellular and in vivo studies to probe disease biology.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2010159-57-4
• MW: 663.83
• Purity: 94.31% (May vary between batches)
• Formula: C₃₂H₄₉N₅O₈S
• SMILES: C([C@@H](NC(COCCOCCOCCOCCN)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1
• Target: E3 Ligase Ligand-Linker Conjugates,Ligands for E3 Ligase
• Solubility: DMSO:153 mg/mL (230.48 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

E3 ligase Ligand-Linker Conjugates 7, E3 ligase Ligand-Linker Conjugates 7 Free Base, AHPC-PEG4-NH2, Ligand for E3 Ligase, LigandforE3Ligase, VHL Ligand-Linker Conjugates 4, VHL, VH032-PEG4-NH2

Compound Identifiers

PubChem CID

124177628