(S,R,S)-AHPC-PEG2-NHS ester

SKU: orb3028698

Description

(S,R,S)-AHPC-PEG2-NHS ester is a synthetic PROTAC linker that combines the E3 ligase ligand with a PEG linker to enhance PROTAC pharmacology. The NHS ester reacts with amine groups, and the hydrophilic PEG spacer increases water solubility.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2757045-58-0
• MW: 715.814
• Formula: C₃₄H₄₅N₅O₁₀S
• SMILES: C(C(NC(CCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)C(C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C=4SC=NC4C)=O)C[C@@H](O)C2
• Target: PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTAC Linker