(S,R,S)-AHPC-PEG2-N3

SKU: orb1307442

Description

This compound is a VHL E3 ligase ligand-linker conjugate, incorporating a (S,R,S)-AHPC ligand connected via a two-unit polyethylene glycol (PEG2) spacer terminated with an azide group. It serves as a key component in the construction of PROTACs and other bifunctional molecules for targeted protein degradation research in both cellular and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2010159-45-0
• MW: 601.72
• Purity: 99.33% (May vary between batches)
• Formula: C₂₈H₃₉N₇O₆S
• SMILES: C([C@@H](NC(COCCOCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
• Target: Ligand for E3 Ligase
• Solubility: DMSO:40 mg/mL (66.48 mM);Ethanol:80 mg/mL (132.95 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VHL Ligand-Linker Conjugates 6, VHL, VH032-PEG2-N3, Ligand for E3 Ligase, LigandforE3Ligase, inhibit, Inhibitor, (S,R,S) AHPC PEG2 N3, (S,R,S)AHPCPEG2N3, (S,R,S)-AHPC-PEG-2-N3, AHPC-PEG2-N3, E3 ligase Ligand-Linker Conjugates 13, E3 Ligase Ligand-Linker Conjugates

Compound Identifiers

PubChem CID

122551829