(S,R,S)-AHPC-C6-PEG3-butyl-N3

• Catalog Number: orb2663754
• Category: Small Molecules
• Description: (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a multifunctional chemical probe featuring an azide group for use in click chemistry. As a building block and template for synthetic targeted protein degradation models, this compound serves as a linker in the E3 enzyme ligand conjugates pivotal for PROTAC research involving the creation of reactive protein degraders, specifically VH032 conjugates. It engages in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC) with molecules containing alkyne groups and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• CAS Number: 2300155-90-0
• Purity: 98.00%
• MW: 757.98
• SMILES: C([C@@H](NC(CCCCCOCCOCCOCCCCCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1
• Formula: C₃₈H₅₉N₇O₇S
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.