SPL-707

SKU: orb1706610

Description

SPL-707 is a potent and selective small molecule inhibitor of signal peptide peptidase-like 2a (SPPL2a), exhibiting an IC50 of 80 nM. This inhibitor is a valuable research tool for investigating the role of SPPL2a in intramembrane proteolysis, with applications in immunological and neurodegenerative disease research using both cellular and animal models.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2195361-33-0
• MW: 505.54
• Formula: C₂₇H₂₈FN₅O₄
• SMILES: Cc1ncc(F)cc1NC(=O)C[C@@H](C1CC1)C(=O)N[C@H]1c2ccccc2C(=O)N2CC3(CC3)CN2C1=O
• Target: Others,Gamma-secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134691740