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sphondin

SKU: orb1220718

Description

Sphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.

Images & Validation

Key Properties

CAS Number483-66-9
MW216.19
Purity>98% (HPLC)
FormulaC12H8O4?
SMILESCOc1cc2ccc(=O)oc2c2ccoc12
TargetCOX
SolubilityIn Vitro: DMSO : 25 mg/mL (115.64 mM)

Bioactivity

In Vitro
Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE2 release.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    99.90%

    483-66-9

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    C12H8O4

    1 mg, 5 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 25 mg, 10 mg
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sphondin (orb1220718)

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% DMSO +
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% Tween 80 +
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Available Sizes

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200 mg
500 mg
5 mg
$ 400.00
10 mg
$ 650.00
25 mg
$ 1,020.00
50 mg
$ 1,400.00
100 mg
$ 1,850.00