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SpHistin
Catalog Number: orb2277120
| Catalog Number | orb2277120 |
|---|---|
| Category | Small Molecules |
| Description | SpHistin, an antimicrobial peptide (AMP), binds to lipopolysaccharide (LPS) and permeabilizes the bacterial membrane. In combination with Rifampicin and Azithromycin, it facilitates increased intracellular uptake of these antibiotics, thereby enhancing their collective bactericidal efficacy against Pseudomonas aeruginosa. |
| MW | 3943.59 |
| Formula | C170H293N61O45S |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide) [orb1981501]
3486.06
C159H250N50O37S
50 mg, 5 mg
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
