SPDP-C6-NHS ester

SKU: orb1988922

Description

SPDP-C6-NHS ester is a heterobifunctional crosslinker used to construct PROTAC molecules for targeted protein degradation. It enables the conjugation of a target protein ligand to an E3 ligase recruiter, facilitating the study of protein function in both cellular and in vivo models via the ubiquitin-proteasome system.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 158913-22-5
• MW: 425.52
• Purity: 98.96% (May vary between batches)
• Formula: C₁₈H₂₃N₃O₅S₂
• SMILES: O=C(ON1C(=O)CCC1=O)CCCCCNC(=O)CCSSC2=NC=CC=C2
• Target: PROTAC Linker,Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.7 mM);DMSO:40 mg/mL (94 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SPDPC6NHS ester, SPDP-C-6-NHS ester, SPDP-C6-NHS ester, SPDP C6 NHS ester, Alkyl/ether

Compound Identifiers

PubChem CID

157808