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Spadin TFA

SKU: orb1981513

Description

Spadin TFA is a potent and selective TREK-1 channel inhibitor (IC50 = 10 nM) derived from a blood propeptide. It enhances serotonergic activity in the dorsal raphe nucleus and promotes hippocampal neurogenesis and CREB phosphorylation, making it a valuable tool for in vitro and in vivo antidepressant mechanism research.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetPotassium Channel,5-HT Receptor
MW2126.36
FormulaC92H143F3N26O24

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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Spadin TFA (orb1981513)

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