Sp-TTPαS

SKU: orb2646096

Description

Sp-TTPαS is a competitive inhibitor of the enzyme SAMHD1, exhibiting a Ki of 46 µM against its TTP hydrolase activity. This small molecule is a valuable research tool for probing SAMHD1's roles in nucleotide metabolism, viral restriction, and autoimmune pathways in cellular and biochemical studies.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 83199-32-0
• MW: 498.23
• Formula: C₁₀H₁₇N₂O₁₃P₃S
• SMILES: O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)S)[C@@H](O)C2)C=C(C)C(=O)N1
• Target: HIV Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

161258