Sofnobrutinib

SKU: orb1744615

Description

Sofnobrutinib (AS-0871) is a potent, orally bioavailable, and selective Bruton's tyrosine kinase (BTK) inhibitor with single-digit nM IC50 values. It demonstrates favorable metabolic stability, weak anaphylactic potential, and has shown anti-inflammatory efficacy in a murine collagen-induced arthritis model, supporting its research use in immunology and autoimmune disease studies.

Key Properties

• CAS Number: 1646608-10-7
• MW: 498.51
• Formula: C₂₆H₂₃FN₈O₂
• SMILES: C(O)C1=C(C=CC=C1C=2N=C(NC3=CN(C)N=C3)N=C(N)N2)N4C(=O)C=5C(C=C4)=CC(=CC5F)C6CC6
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

87056204