SNIPER(ER)-110

SKU: orb1987734

Description

SNIPER(ER)-110 comprises a cIAP1 ligand and an estrogen ligand connected by a linker. SNIPER(ER)-51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 1122.39
• Formula: C₆₆H₈₃N₅O₁₁
• SMILES: O=C([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)C[C@@H](OC3=CC=CC(OCCOCCOCCOCC(N(C)CCOC4=CC=C(/C(C5=CC=C(O)C=C5)=C(C6=CC=CC=C6)/CC)C=C4)=O)=C3)C1)N[C@@H]7CCCC8=C7C=CC=C8
• Target: SNIPERs,Estrogen Receptor/ERR,Others

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SNIPERs,Estrogen Receptor/ERR,Others