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Catalog Number | orb67068 |
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Category | Antibodies |
Description | Rabbit polyclonal to SMARCA5.SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5(SMARCA5) is a member of the SWI/SNF family of proteins. Members of this family have helicaseand ATPase activities and are thought to regulate transcription of certain genes by altering thechromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling andspacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. It hasbeen shown that SMARCA5 is overexpressed in CD34-positive erythrocyte progenitor cells in acutemyeloid leukemia, while its down-regulation correlates with hematologic remission followingchemotherapy. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse |
Immunogen | N-terminal region of human SMARCA5 |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 122 |
UniProt ID | O60264 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-SMARCA5 antibody,anti-SWI antibody,anti-SNFre Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from mouse MEF using SMARCA5 antibody