SKLB 610

SKU: orb1307214

Description

SKLB610 is a novel multi-targeted tyrosine kinase inhibitor. At 10 µM, it potently inhibits VEGFR2 (97%), FGFR2 (65%), and PDGFR (55%) in biochemical assays. This profile supports its research use in studying angiogenesis and tumor growth in both cellular and animal models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1125780-41-7
• MW: 415.37
• Purity: 99.83% (May vary between batches)
• Formula: C₂₁H₁₆F₃N₃O₃
• SMILES: O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(=O)C3=CC(C(F)(F)F)=CC=C3)C=C2
• Target: FGFR,PDGFR,VEGFR
• Solubility: DMSO:50 mg/mL (120.37 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PDGFR, FGFR, SKLB610, SKLB-610, SKLB 610, VEGFR

Compound Identifiers

PubChem CID

25230662