SJ000063181

SKU: orb1689383

Description

SJ000063181 is a potent, cell-permeable BMP signaling activator (EC50 ≤1 µM). This chemical probe is particularly valuable for studying BMP pathway roles in developmental biology and disease models, as demonstrated by its effective use in zebrafish embryo studies.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 945189-68-4
• MW: 296.72
• Purity: 99.94%
• Formula: C₁₄H₁₄ClFN₂O₂
• SMILES: CC(C)Cc1cc(no1)C(=O)Nc1ccc(F)c(Cl)c1
• Target: TGF-beta/Smad
• Solubility: DMSO:90 mg/mL (303.32 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (11.12 mM)

Bioactivity

• Target IC50:
  BMP:≤1 µM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

bone morphogenetic protein (BMP), TGF-β/Smad, TGFβ, TGF-beta/Smad, TGFbeta/Smad, TGF-beta, TGFb, TGF-b/Smad, TGFbeta, Smad

Compound Identifiers

PubChem CID

17253337