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Sirtuin modulator 1

SKU: orb1309092

Description

SRT3025 Hydrochloride is a potent SIRT1 activator with an EC1.5 below 1 μM. This small molecule is utilized in research exploring aging, metabolism, and cellular stress resistance, with applications in both in vitro and in vivo experimental models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

CAS Number2070015-26-6
MW606.2
Purity99.63%
FormulaC31H32ClN5O2S2
SMILESCl.COCCCc1sc(nc1C(=O)Nc1ccccc1-c1nc2cc(CN3CCCC3)cnc2s1)-c1ccccc1
TargetSirtuin
SolubilityDMSO:12 mg/mL (19.8 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.65 mM)

Bioactivity

Target IC50
SIRT1:1 μM (EC1.5)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, Sirtuin modulator 1, Sirtuin modulator1, Sirtuin modulator-1, Sirtuin, SIRT1, SRT3025 Hydrochloride, SRT-3025 Hydrochloride, SRT 3025 Hydrochloride

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Key Properties

No computed properties available.

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Protocol Information

Sirtuin modulator 1 (orb1309092)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 90.00
25 mg
$ 130.00
50 mg
$ 280.00
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