Simocyclinone D8

SKU: orb2645993

Description

Simocyclinone D8 is a dual-function anthracycline antibiotic that inhibits bacterial DNA gyrase, providing activity against Gram-positive bacteria. Its antitumor properties, demonstrated in vitro, arise from this topoisomerase inhibition, suppressing the growth of various cancer cell lines.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 301845-97-6
• MW: 932.27
• Formula: C₄₆H₄₂ClNO₁₈
• SMILES: O[C@@]12[C@@]34[C@@](O3)([C@H](O)C=5C(C4=O)=CC=C(C5O)[C@H]6C[C@@H](OC(/C=C/C=C/C=C/C=C/C(NC7=C(O)C=8C(OC7=O)=C(Cl)C(O)=CC8)=O)=O)[C@H](OC(C)=O)[C@@H](C)O6)[C@@H](O)C[C@]1(O)CC(C)=CC2=O
• Target: Antibacterial,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

54736483