SIAIS125

SKU: orb2814923

Description

SIAIS125 is an irreversible covalent PROTAC degrader targeting the epidermal growth factor receptor (EGFR). It has demonstrated potent degradation of EGFR in cellular assays and shows potential for investigating resistance mechanisms in non-small cell lung cancer research models.

Key Properties

• CAS Number: 2600730-82-1
• MW: 854.33
• Formula: C₄₃H₄₅ClFN₉O₇
• SMILES: O=C(C=C)NC1=CC=2C(=NC=NC2NC3=CC=C(F)C(Cl)=C3)C=C1OCCCN4CCN(C(=O)CCCCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156058925