SG3199

SKU: orb1909128

Description

SG3199 is a potent PBD dimer that covalently binds the DNA minor groove to form interstrand cross-links. This mechanism underlies its significant cytotoxicity against diverse human cancer cell lines in vitro, supporting its investigation as a payload in antibody-drug conjugates for oncology research.

Research Area

Molecular Biology

Key Properties

• CAS Number: 1595275-71-0
• MW: 584.66
• Formula: C₃₃H₃₆N₄O₆
• SMILES: [H][C@@]12CC(C)=CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4N=C[C@]5([H])CC(C)=CN5C(=O)c4cc3OC)cc1N=C2
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90132565